Are polioviruses a cause of schizophrenia?

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NSC-induced D-neurons are decreased in striatum of schizophrenia: Possible cause of mesolimbic dopamine hyperactivity

Neural stem cell (NSC) hypofunction is an etiological hypothesis of schizophrenia. Although dopamine (DA) dysfunction is also a widely accepted hypothesis, molecular background of mesolimbic DA hyperactivity has not yet been well known. Here, the author proposes “D-cell hypothesis”, accounting for molecular basis of mesolimbic DA hyperactivity of schizophrenia, by NSC hypofunction and decrease ...

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ژورنال

عنوان ژورنال: British Journal of Psychiatry

سال: 1992

ISSN: 0007-1250,1472-1465

DOI: 10.1192/bjp.161.3.427